71 Infection Control CNA Practice Questions

1. When performing hand hygiene, what is the minimum amount of time you should wash your hands with soap and water?

According to CDC guidelines and NNAAP standards, hands should be washed with soap and water for at least 20 seconds to effectively remove microorganisms. 10 seconds is insufficient for proper cleansing. 30 and 60 seconds are longer than necessary for routine handwashing.

2. Which of the following situations requires handwashing before donning gloves?

Hands must be washed before eating, before using the bathroom, and before and after patient care to prevent the spread of infection in all situations. Proper hand hygiene is essential in every circumstance to maintain infection control standards.

3. You notice a patient's isolation sign indicates contact precautions. What is the primary reason for this isolation type?

Contact precautions are used when a patient has an infection spread through direct contact with the patient or contaminated surfaces. Airborne precautions prevent airborne transmission, droplet precautions prevent droplet transmission, and standard precautions address bloodborne pathogen exposure. Contact precautions require gloves and gowns when entering the room.

4. When should you change your gloves during patient care?

Gloves should be changed when moving between different body sites or tasks on the same patient (for example, after helping with toileting and before assisting with meals). While changing gloves only at shift end and only when visibly soiled are incorrect, the most comprehensive answer is changing between different body sites/tasks. This prevents cross-contamination during care.

5. Which piece of personal protective equipment (PPE) should be put on first when entering an isolation room?

The proper order for donning PPE is: gown first, then mask, then eye protection, and finally gloves last. The gown should be put on first to prevent contamination of underlying clothing. Gloves are applied last to cover the wrist of the gown.

6. What is the correct order for removing PPE (doffing) when leaving an isolation room?

The correct PPE doffing (removal) order per CDC and NNAAP guidelines is: gloves first (most contaminated), then eye protection, then gown, then mask last (to maintain respiratory protection until the very end). Gloves come off first because they have the most surface contamination from direct patient care. Eye protection is removed before the gown because it is easier to remove without contaminating the face when gloves are already off. The mask is removed last so respiratory protection is maintained throughout the doffing process.

7. A patient has diarrhea caused by Clostridioides difficile (C. difficile). Which precaution type is most appropriate?

C. difficile is transmitted through contact with contaminated feces and surfaces, so contact precautions are required. This includes wearing gloves and a gown. Droplet and airborne precautions are not appropriate for C. difficile as it is not spread through respiratory droplets or air. Standard precautions alone are insufficient.

8. When is it appropriate to use hand sanitizer instead of handwashing with soap and water?

Hand sanitizer can be used when hands are not visibly soiled and soap and water are unavailable. However, if hands are visibly soiled with blood, body fluids, or other contaminants, soap and water must be used as sanitizer is less effective in these situations. Sanitizer should not be the first choice when water is available.

9. A patient is on airborne precautions for suspected tuberculosis. What type of mask should you wear when entering the room?

An N95 respirator mask provides the appropriate level of protection for airborne precautions such as tuberculosis. A surgical mask is not sufficient for airborne pathogens as it does not filter inhaled air. Cloth masks and no mask are inappropriate and would not provide protection against airborne transmission.

10. What is the primary purpose of standard precautions?

Standard precautions are based on the principle that all blood, body fluids, secretions, and excretions may contain pathogens, regardless of the patient's diagnosis or whether an infection is known. This approach should be used with all patients at all times. It is not limited to only bloodborne pathogens or only known infections.

11. You accidentally stick yourself with a contaminated needle. What should you immediately do first?

You should immediately wash the area with soap and water. While reporting to your supervisor is important, it comes after first aid. Applying a tourniquet is not appropriate for needlestick injuries. Squeezing the wound is generally not recommended as it can increase tissue damage. Immediate cleansing is the first priority.

12. When disposing of sharps, what must you use?

All sharps (needles, syringes, lancets, etc.) must be placed in a designated, puncture-resistant sharps container. Using regular trash, toilets, or other waste receptacles is dangerous and against infection control protocol. This protects healthcare workers and environmental safety.

13. A patient has a productive cough and fever. The patient is suspected of having influenza. What precautions should be implemented?

Influenza is spread through respiratory droplets, so droplet precautions are appropriate. This includes wearing a surgical mask and maintaining distance from the patient. Contact precautions are used for conditions spread through touch, airborne precautions for diseases like tuberculosis, and standard precautions alone are insufficient for flu.

14. What should you do if you tear your glove while providing patient care?

You should immediately remove the torn glove and put on a new pair to maintain infection control. Continuing with a torn glove compromises protection and creates a contamination risk. Tape is not an appropriate solution. Handwashing alone does not replace the need for intact gloves during patient care.

15. Which of the following is a correct principle of infection control?

All equipment and surfaces that contact patients must be cleaned and disinfected between patients to prevent cross-contamination. Touching your face with gloved hands can spread pathogens. Gloves should never be reused. Handwashing is required throughout the day in multiple situations, not just before eating.

16. A patient requires droplet precautions. Where should this patient ideally be placed?

A patient on droplet precautions should ideally be placed in a private room with the door closed to prevent respiratory droplets from reaching other patients. If a private room is unavailable, specific cohorting (grouping patients with the same infection) may be used. Placing them in any shared room without proper precautions risks spreading infection.

17. What does the acronym PPE stand for?

PPE stands for Personal Protective Equipment. This includes gloves, masks, gowns, and eye protection that healthcare workers wear to protect themselves and patients from infection. The other options are incorrect terms not used in healthcare infection control.

18. When should you perform hand hygiene before putting on gloves?

Hands should be cleaned before every patient contact, before donning gloves. Gloves do not eliminate the need for handwashing; they are an additional barrier. Even if hands don't appear dirty, they may harbor microorganisms. Handwashing must occur throughout the shift, not just at the beginning.

19. A patient with chickenpox (varicella) is admitted. What type of precautions are required?

Chickenpox (varicella) requires both airborne and contact precautions because the varicella-zoster virus spreads through airborne particles (microscopic droplet nuclei that remain suspended in air) as well as direct contact with rash lesions. Airborne precautions include placing the patient in a negative-pressure room and using an N95 respirator. Droplet precautions alone (A) are insufficient. Contact precautions alone (B) do not address airborne spread. Airborne precautions alone (C) do not address contact transmission from lesions.

20. What is the correct technique when removing a contaminated gown?

A contaminated gown should be peeled away from the body, rolling it inward as you remove it. This prevents the contaminated outer surface from touching your skin or clothing. Pulling from the neckline, slow removal, and folding from the outside don't address proper containment of contaminants.

21. How long should you avoid touching your face after removing gloves from a patient with a respiratory infection?

You should wash your hands immediately after removing gloves before touching your face. Handwashing removes any pathogens that may have contaminated your hands despite glove use. You should not wait or touch your face before washing hands, as this risks introducing pathogens to mucous membranes.

22. What is the most common route of transmission of healthcare-associated infections (HAIs)?

Contaminated hands of healthcare workers are the most common route of transmission for healthcare-associated infections. This is why proper hand hygiene and glove use are so critical. While airborne, environmental, and bloodborne transmission occur, hand contamination accounts for the majority of HAI transmissions.

23. A patient on contact precautions needs to be transported to radiology. What should you do?

When transporting a patient on contact precautions, you should use appropriate PPE, alert the receiving department, and take measures to prevent contamination during transport. The patient should maintain precautions, and staff at receiving areas must be informed. Ignoring precautions during transport spreads infection beyond the patient's room.

24. Which situation would NOT require a change of gloves?

Gloves do not need to be changed when moving between clean, non-contaminated areas on the same patient during routine care with no wounds or soiling present — such as bathing one arm and then the other. All other options involve moving from a highly contaminated task (wound, toileting, IV catheter) to a clean task or different body area, which requires a glove change to prevent cross-contamination. Standard precautions require changing gloves between contaminated and clean body sites and between different care tasks.

25. What is the primary reason for using standard precautions with every patient, regardless of diagnosis?

Standard precautions are used with every patient because you cannot always know a patient's infection status or if they are carrying pathogens. Some patients may be asymptomatic carriers or undiagnosed. Using standard precautions universally is more effective than trying to identify which patients need protection. It protects against all potential pathogens, not just bloodborne ones.

26. When washing hands, what is the minimum recommended length of time you should scrub with soap and water?

The CDC recommends washing hands for at least 20 seconds to effectively remove germs and pathogens. 10 seconds is too short to be effective. 40 and 60 seconds are longer than necessary and waste time.

27. Which of the following is the most important time to wash your hands as a nursing assistant?

Before and after patient contact is critical for infection control to prevent spreading pathogens between patients and to yourself. While after using the restroom and before eating are important, before and after patient care is the priority in healthcare settings. Beginning of shift is too vague.

28. What should you do if soap and water are not available when caring for a patient?

Alcohol-based hand sanitizer with at least 60% alcohol is an acceptable alternative when soap and water are not available. Waiting is impractical in patient care. Wiping on cloth is ineffective. Gloves alone do not eliminate the need for hand hygiene.

29. You are assisting a patient with bedside hygiene and notice they have visible blood on their skin. What type of PPE should you wear at minimum?

Blood exposure requires gloves and a gown at minimum under standard precautions. Gloves alone do not provide adequate protection for potential splashing. Face shield and goggles are added only if splashing is likely. Full PPE listed in choice D is excessive for this scenario.

30. When removing contaminated gloves, what is the correct first step?

You should pinch the outside of one glove near the wrist (avoiding bare skin contact) and peel it off, turning it inside-out. Removing both at once is incorrect procedure. Washing before removal doesn't make sense. Grasping the palm risks contamination of bare skin.

31. A patient is on contact precautions for a skin infection. What does this mean regarding your PPE?

Contact precautions require gloves and gown for anyone having direct contact with the patient. Respirators are for airborne precautions, not contact. Gloves should be worn for all direct contact, not just non-intact skin. Antibiotics don't eliminate the need for precautions during treatment.

32. What is the primary purpose of using standard precautions?

Standard precautions are based on treating all blood and body fluids as potentially infectious, regardless of the patient's diagnosis. They apply to all patients, not just immunocompromised ones. Standard precautions work alongside specific isolation precautions when needed. While they help protect visitors, that's not the primary purpose.

33. You accidentally splash patient blood into your eye. What should you do immediately?

You must immediately rinse the eye with water for at least 15 seconds and report the bloodborne pathogen exposure incident for proper follow-up and documentation. Rubbing the eye can cause more damage. Waiting to see if symptoms develop delays necessary medical evaluation. Ointment and bandage are not appropriate first aid for an eye exposure.

34. A patient is in droplet precautions for influenza. Which action is most important for preventing transmission?

Droplet precautions require a mask for close contact (within 3-6 feet) and keeping the door closed. Patients don't wear respirators; healthcare workers do. Negative pressure is for airborne precautions. Complete visitor restriction is too strict for droplet precautions; visiting is allowed with precautions.

35. Which of the following statements about N95 respirators is correct?

N95 respirators filter at least 95% of airborne particles, which is how they get their name. Many facilities have moved to single-use for infection control. They are used for airborne precautions, not contact/droplet. Fit testing is required to ensure proper seal and effectiveness.

36. You notice a patient has signs of a respiratory infection but has not been placed on precautions yet. What should you do?

You should immediately notify the nurse so they can assess the patient and implement appropriate precautions if indicated. Standard precautions alone may be insufficient for a respiratory infection. Waiting or taking independent action delays proper care and increases transmission risk.

37. When should a surgical mask be changed?

Surgical masks should be changed every 2-4 hours or when they become damp or soiled, as moisture reduces their effectiveness. Every 8 hours is too long. Waiting until visibly dirty is too late for protection. Weekly reuse is not appropriate for infection control.

38. A patient with MRSA (methicillin-resistant Staphylococcus aureus) is being admitted to your facility. What precautions should be implemented?

MRSA requires contact precautions because it spreads through direct or indirect contact with contaminated surfaces or skin. It does not require airborne or droplet precautions. Standard precautions alone are insufficient for MRSA.

39. You are wearing a gown during patient care. When should you remove it?

The gown should be removed immediately after patient contact, before leaving the room, to prevent contamination of other areas. Removing it before leaving but after hand washing risks recontamination. Keeping it on until end of shift spreads pathogens throughout the facility.

40. What is the correct order for removing PPE?

The correct PPE removal (doffing) order per CDC and NNAAP guidelines is: gloves → eye protection → gown → mask. Remove gloves first because they are the most contaminated. Eye protection comes next — easier to remove safely without gloves, and before the gown. The gown is removed third. The mask is removed last to maintain respiratory protection until everything else is off. Hand hygiene should be performed after removing gloves and again after removing the mask.

41. A patient sneezes while you are providing direct care without a mask. What should you happen next?

When a patient sneezes during direct care without a mask, the immediate priority is protective action: step back to increase distance and put on a mask to reduce further exposure risk. Hand hygiene should also be performed promptly. Reporting and documentation (D) may be appropriate if symptoms develop or if the patient has a known or suspected communicable condition, but immediate protective action comes first for a single unprotected exposure. Ignoring the exposure (A) is never appropriate. Hand washing and monitoring (C) addresses hygiene but delays the immediate protective response.

42. Which situation would require airborne precautions?

Tuberculosis (TB) and chickenpox (varicella) require airborne precautions because their pathogens spread via airborne particles (droplet nuclei) that can remain suspended in the air for extended periods. Airborne precautions include a negative-pressure room and N95 respirator. Influenza (A) is transmitted via large respiratory droplets and typically requires droplet precautions, not airborne — standard seasonal influenza does not warrant airborne precautions. Selecting only B and C is correct.

43. You accidentally stick yourself with a used needle from a patient's bedside. What is the first thing you should do?

Immediately wash the wound with soap and water, then report it. Squeezing promotes bleeding which can increase infection risk. While reporting is essential, washing first is the immediate action. A bandage without washing is insufficient. All of these steps are important, but washing comes first.

44. A patient on airborne precautions needs to leave their room for a procedure. What should the patient wear?

The patient should wear a surgical mask when leaving the room to protect others from airborne particles. The patient does not need an N95. Assuming other rooms have precautions is unsafe. A gown and gloves are contact precautions, not respiratory protection.

45. What is the most common way infections are transmitted in healthcare settings?

Contaminated hands and surfaces are the most common transmission route in healthcare. While airborne transmission occurs, it's less common. Food/water and insect vectors are rare in healthcare facilities. This is why hand hygiene is the foundation of infection control.

46. A colleague is about to care for a patient with hepatitis B without wearing gloves. What should you do?

You should politely remind your colleague of the infection control requirement. Hepatitis B is transmissible through blood and body fluid exposure. Saying nothing is a safety risk. Immediately reporting may be excessive if a reminder works, though reporting is appropriate if unsafe practice continues.

47. When donning PPE, what is the correct order to put items on?

The correct donning order is: gown first (largest barrier, protects clothing and skin), then mask or respirator (positioned before goggles so the mask ties don't contaminate the goggles), then eye protection, and finally gloves last (so they cover the wrists of the gown). This sequence ensures each item is applied cleanly without contaminating the next. A common mistake is putting on the mask before the gown — always gown first.

48. A patient has a urinary tract infection (UTI) and is not on isolation precautions. Should you wear any special PPE?

UTIs do not require special precautions beyond standard precautions. UTIs are not communicable in the way that contact or airborne diseases are. Standard precautions with hand hygiene and appropriate handling of urine are sufficient. Fever alone doesn't indicate airborne transmission for a UTI.

49. You are assisting a patient with dementia who keeps removing their isolation precaution signs. What should you do?

You should replace the signs and notify the nurse, who can provide appropriate care and possibly assign more frequent observation. Allowing sign removal defeats infection control efforts. Restraints are not an appropriate solution to this problem. Documentation alone without action is insufficient for patient and staff safety.

50. What is the most effective way to prevent healthcare-associated infections (HAIs)?

Hand hygiene is the single most effective and evidence-based method for preventing HAIs. Prophylactic antibiotics can lead to resistance and aren't appropriate for all patients. Masks and visitor restrictions may help but are secondary to hand hygiene. This is supported by CDC and WHO guidelines.

51. When washing your hands, what is the minimum recommended length of time you should scrub with soap and water?

The CDC and WHO recommend washing hands with soap and water for at least 20 seconds to effectively remove pathogens. 10 seconds is too brief to be effective. 45 seconds and 1 minute are longer than necessary, though not harmful. Twenty seconds is the evidence-based standard for adequate handwashing.

52. Which of the following is the MOST important time to perform hand hygiene?

Handwashing before direct patient contact is essential to prevent transmitting pathogens to vulnerable patients. After eating and before leaving shift are good practices but less critical. Hands should be washed even when not visibly soiled, as microorganisms are not always visible to the naked eye.

53. You are caring for a patient on contact precautions. Which item of PPE should you put on FIRST when entering the room?

The correct order for donning PPE is: gown first, then mask, eye protection, and gloves last. The gown should be put on first to protect your clothing. Gloves are put on last so they can cover the wrists of the gown. Masks and eye protection go on before gloves.

54. When should you remove gloves during patient care?

Gloves should be changed between tasks and different patient contacts to prevent cross-contamination. Wearing the same gloves throughout your shift defeats the purpose of using them. Slight moisture doesn't always indicate they need removal, but contamination and task changes do. Standard precautions require frequent glove changes.

55. You have a small cut on your hand. What should you do before providing patient care?

A cut should be covered with a waterproof bandage, and then gloves should be worn for patient care. This protects both you and the patient. Hand lotion does not create a barrier. Handwashing is still necessary even with a cut. Requesting reassignment is unnecessary if the cut is properly covered and protected.

56. Which of the following best describes standard precautions?

Standard precautions are infection control practices applied to ALL patients, regardless of known infection status, because many patients may be asymptomatic carriers. They are not limited to known infections or isolation rooms. They must be performed consistently throughout the shift, not just once daily.

57. When performing hand hygiene, you should wash up to where on your arms?

Hand hygiene should include washing hands, fingers, and wrists. The wrists and lower forearms are common areas where pathogens can collect. Elbows are not typically included in routine handwashing. Just the palms or hands alone is insufficient for adequate hygiene.

58. You notice a patient in your care has symptoms of a respiratory infection. What should you do FIRST?

The first action should be to notify the nurse and follow facility protocol, as only authorized personnel can implement isolation precautions. You should not attempt to isolate a patient independently. While PPE will likely be needed, the nurse must assess the situation first. Standard precautions alone may be insufficient for respiratory symptoms.

59. When should you perform hand hygiene after removing gloves?

Hands should be washed immediately after removing gloves, as gloves can have microscopic tears and hands may have been contaminated during removal. Waiting until the end of shift allows pathogens to spread. Feeling wet is not an indicator of cleanliness. Glove use does not eliminate the need for handwashing.

60. Which situation requires you to change your gloves?

Gloves must be changed both between different patients AND when moving from contaminated to clean areas on the same patient to prevent cross-contamination. Changing gloves only between patients is insufficient because you can spread pathogens on the same patient from soiled to clean areas.

61. What is the proper way to don a face mask?

A face mask must cover both the nose and mouth securely to be effective in preventing respiratory droplet transmission. Covering only the mouth or nose is ineffective. Loose ties compromise the seal and protective function. Proper placement is essential for the mask to work.

62. You are assisting a patient with hygiene and get splashed with body fluid. What should you do?

You should stop immediately, clean the exposed area, and report the incident to your nurse, as this is a potential bloodborne pathogen exposure that must be documented. Delaying washing increases infection risk. A tissue or hand sanitizer alone is insufficient for a splash exposure. Your nurse needs to know about this incident for proper follow-up.

63. Which of the following is NOT part of standard precautions?

Standard precautions include handwashing, PPE use, and safe injection practices. Additional isolation precautions (such as droplet, airborne, or contact precautions) go beyond standard precautions and are used for specific conditions. Isolation precautions are separate from standard precautions, not part of them.

64. You are wearing a gown during patient care. When should you remove it?

A gown should be removed before leaving the patient's room to prevent spreading contamination to other areas. Keeping a gown on until the end of shift can spread pathogens throughout the facility. Visibility of soiling is not the only indication for removal. Comfort is not a factor in infection control decisions.

65. When using hand sanitizer, how much product should you use?

Enough hand sanitizer should be used to coat all surfaces of the hands and rubbed until dry. A tiny drop is insufficient to cover all areas. Using excessive amounts is wasteful and not necessary. The amount does matter for effectiveness—all surfaces must be covered.

66. What is the primary purpose of wearing gloves in patient care?

The primary purpose of gloves is to prevent the spread of infection by creating a barrier. While gloves help keep hands clean and create a physical barrier, their main function is infection prevention. Gloves are not primarily for patient comfort, though they may contribute to it.

67. A patient is on airborne precautions. Which type of mask must you wear?

An N95 respirator is required for airborne precautions because it filters smaller airborne particles. A standard surgical mask does not provide adequate protection for airborne pathogens. Airborne precautions specifically require N95 respirators, not just any mask. A mask is definitely needed for airborne precautions.

68. Which body fluids require the use of gloves according to standard precautions?

Standard precautions require gloves for contact with blood, all body fluids (except sweat), secretions, excretions, non-intact skin, and mucous membranes. Sweat is not considered a significant transmission risk unless visibly contaminated with blood. All potentially infectious body fluids require glove use, not just blood or selected fluids.

69. After removing all PPE, in what order should you perform hand hygiene and return to work areas?

The correct sequence is to remove PPE first, then immediately perform hand hygiene before returning to work areas or touching other surfaces. This prevents contamination from any residual pathogens. Returning to work areas before handwashing can spread pathogens. Handwashing while gloved is less effective. Hand hygiene after PPE removal is mandatory, not optional.

70. You are assisting a patient who is on contact precautions due to a methicillin-resistant Staphylococcus aureus (MRSA) infection. After removing your gloves, what is the most important next step in proper infection control?

Washing your hands with soap and water immediately after removing gloves is the most important next step in infection control. Hand hygiene is the single most effective measure to prevent the spread of infection. Answer A is incorrect because gloves should be removed before the gown in proper PPE doffing sequence (gloves → eye protection → gown → mask) — removing the gown first risks contaminating your hands. Answer C is incorrect because soap and water are more effective than hand sanitizer for contact precautions and certain pathogens such as C. difficile spores. Answer D is incorrect because hand hygiene should be performed immediately after glove removal, not delayed.

71. Which of the following statements is correct?

The correct answer is B. Hand hygiene must always be performed before putting on gloves and immediately after removing them — gloves do not replace hand hygiene. Choice A is false: gloves are a barrier, not a hand-hygiene substitute. Choice C is false: contact precautions typically require gloves and a gown, not gowns alone. Choice D is false: alcohol-based hand rub is not sufficient when hands are visibly soiled — soap and water must be used in that case.